In recent years there has been a great increase in the cases of multidrug resistant bacterial infections. These infections are becoming more dangerous as fewer known antibiotics are able to be used to treat them. One of these worrisome bacteria is Acinetobacter baumannii. A. baumannii has become a major contributor to nosocomial infections in recent years. With its ability to attach to sterile medical surfaces, produce a biofilm, and be resistant to disinfectants it is growing increasingly difficult to treat. Micrococcus luteus, while not typically thought of as a pathogen, is also capable of producing biofilm and is showing signs of developing antibiotic resistance as well. Because of this it is important to investigate new ways of treating antibiotic resistant bacteria. One way to do so is with bacteriophage therapy that will to target specific pathogens and clear the infection. Bacteriophage are able to diffuse through biofilms and less prone to have bacteria become resistant to them. This research looks at methods used to isolate novel bacteriophage for A. baumannii and M. luteus from dairy cattle feces.
Keywords: Antibiotic resistance, Acinetobacter baumannii, Micrococcus luteus, Bacteriophage therapy |