Many environmental elements can have an impact on our health, with eating being a
prominent one. In this study, we tracked the accumulation of 30 essential metals and
electrolytes consumed in a regular diet over a lifetime in the heart, liver, lung, spleen,
kidney, and whole brain of healthy adult female rats (120 days). Furthermore, we
collected the elemental distributions in these vital organs in rats that were given an excess
amount of Mn2+ in their normal diet (drinking water). Thus, we could estimate how high
Mn intake influenced the buildup of these metals and electrolytes in the important organs
of rats. With this information, we projected how these elements and electrolytes may be
distributed in humans as well as how heavy metal ingestion, such as Mn, may impact
elemental distributions/accumulations in the similar six human organs. This is a model to
project elemental distribution in the human body using animal data.
Key Words: Human, Rat, Organ, Element, Ingestion, Heavy metal |