| Covid-19 caused by SARS-CoV-2 is a global wide pandemic with illness and death reaching into the millions. With hundreds of different testing methods implemented in order to diagnose this disease, Boise State University implemented two: the TaqPath COVID-19 Combo Kit and SalivaDirect. The TaqPath COVID-19 Combo kit used nasopharyngeal swabs with healthcare professionals having to collect them from the university’s community. A validation for a more cost effective and sensitive method of testing took place in November 2020 that changed the sample type from nasopharyngeal to saliva and had henceforth broadened the university’s testing range. The SalivaDirect testing method was performed on known positive and negative saliva samples on November 27th 2020, and December 11th, 2020 on the university’s Quant Studio 5 PCR instruments. Testing found that SalivaDirect was more accurate and precise than the previously used TaqPath, thus lowering the cost and providing quality results to those tested. Key Words: Saliva Direct, TaqPath COVID-19 Combo Kit, Covid-19, SARS-CoV-2, PCR, Validation |